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Aelin Therapeutics will be presenting at the annual TPD event in London in March 2023

| Events | No Comments
Our CSO, Rie Schultz Hansen will be presenting Aelin Therapeutics at the upcoming annual TPD event in London in March 2023.

Aelin Therapeutics Will Be At The Upcoming Biotech Showcase And JPM In San Francisco

| Events, General news | No Comments
Aelin Therapeutics Will Be At The Upcoming Biotech Showcase And JPM In San Francisco

Aelin Therapeutics will be presenting at Bio€quity Europe 2023 in Dublin

| Events, General news | No Comments
Proud to be selected as ‘Presenting Company with live presentation during the 23rd Bio€quity Europe Conference, in May 2023 in Dublin. #BioEquity #lifesciences #partnering #innovation
Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins

Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins

| Scientific publications | No Comments
We have developed a statistical mechanics algorithm, TANGO, to predict protein aggregation. TANGO is based on the physico-chemical principles of b-sheet formation, extended by the assumption that the core regions…
Nature Communications 2020 Michiels

Reverse engineering synthetic antiviral amyloids

| Scientific publications | No Comments
Human amyloids have been shown to interact with viruses and interfere with viral replication. Based on this observation, we employed a synthetic biology approach in which we engineered virus-specific amyloids…

Aggregating sequences that occur in many proteins constitute weak spots of bacterial proteostasis

| Anti bacterials, Scientific publications | No Comments
Aggregation is a sequence-specific process, nucleated by short aggregation-prone regions (APRs) that can be exploited to induce aggregation of proteins containing the same APR. Here, we find that most APRs…

De novo design of a biologically active amyloid

| High value, undruggable targets, Scientific publications | No Comments
Amyloid aggregation is driven by short sequences within proteins that self-assemble into characteristic amyloid structures. About 30 human proteins are implicated in amyloid-associated diseases, but many more contain short sequences…