News & Events
Proud to be selected as ‘Presenting Company Class of 2022’ with live presentation during the ‘Hot Topics Track’ at the 22nd Bio€quity Europe Conference, hosted by BioCentury and EBD (May 16th -…
Please join Els Beirnaert, CEO, presenting on April 13th and 14th 2021
Funding will enable accelerated development of unique Pept™-in-based cancer therapeuticsLeuven, BELGIUM – 9 July 2020 – Aelin Therapeutics NV, an emerging biotechnology company focused on the discovery and development of…
We have developed a statistical mechanics algorithm, TANGO, to predict protein aggregation. TANGO is based on the physico-chemical principles of b-sheet formation, extended by the assumption that the core regions…
Human amyloids have been shown to interact with viruses and interfere with viral replication. Based on this observation, we employed a synthetic biology approach in which we engineered virus-specific amyloids…
Aggregation is a sequence-specific process, nucleated by short aggregation-prone regions (APRs) that can be exploited to induce aggregation of proteins containing the same APR. Here, we find that most APRs…
Amyloid aggregation is driven by short sequences within proteins that self-assemble into characteristic amyloid structures. About 30 human proteins are implicated in amyloid-associated diseases, but many more contain short sequences…
